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Springer Proceedings in Materials ; 22:111-123, 2023.
Article in English | Scopus | ID: covidwho-20242302

ABSTRACT

This review article highlights the importance of messenger ribonucleic acid (mRNA) vaccines and how it has been developed to fight against various diseases such as, human immunodeficiency virus (HIV), rabies, cancer treatments, and coronavirus (Covid-19). During the past two years, covid-19 has become a worldwide pandemic, and the mRNA has played a major role in the manufacturing of its vaccine. We have highlighted the technology behind the development of mRNA vaccine, synthesis, and working of the lipid nanoparticles (LNPs). This mRNA vaccine produces a duplicate of a molecule that corresponds to a viral protein for producing an immune response, and these are given to us in a series of shots designed to protect us from developing a disease. The LNPs which carry the mRNA protein prevent the degradation of it and maintain more constant serum levels. In addition, this review article specifically mentions HIV, rabies, cancer, covid-19 and how these are important in the treatment of these diseases. This review article further highlights the mRNA vaccines for the survival of human beings against various deadly diseases in the near future. © 2023, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

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